eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin
Background: Hypoxia and sweers island for sale consequent production of vascular endothelial growth factor A (VEGFA) promote blood vessel leakiness and edema in ocular diseases.Anti-VEGFA therapeutics may aggravate hypoxia; therefore, therapy development is needed.Methods: Oxygen-induced retinopathy was used as a model to test the role of nitric ox