ENOS-INDUCED VASCULAR BARRIER DISRUPTION IN RETINOPATHY BY C-SRC ACTIVATION AND TYROSINE PHOSPHORYLATION OF VE-CADHERIN

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Background: Hypoxia and sweers island for sale consequent production of vascular endothelial growth factor A (VEGFA) promote blood vessel leakiness and edema in ocular diseases.Anti-VEGFA therapeutics may aggravate hypoxia; therefore, therapy development is needed.Methods: Oxygen-induced retinopathy was used as a model to test the role of nitric ox

read more



The single-dose Janssen Ad26.COV2.S COVID-19 vaccine elicited robust and persistent anti-spike IgG antibody responses in a 12-month Ugandan cohort

IntroductionThe study investigation examined the immune response to the Janssen Ad26.COV2.S COVID-19 vaccine crewman talc within a Ugandan cohort, specifically targeting antibodies directed against spike (S) and nucleocapsid (N) proteins.We aimed to examine the durability and robustness of the induced antibody response while also assessing occurren

read more